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Friday evening I met Dr. Halimah (deputy dean of the Faculty of Communication & Media Studies) for the first time. She and Kiran were at KLCC (huge shopping mall at the ), buying tickets for Saturday to a 3-and-a-half-hour Bollywood movie (I decided against joining them). We had dinner at KLCC, and afterward Kiran drove us around so I could see the sights of KL at night.
We went shopping at a night market in the Chinatown area, and both Halimah and Kiran bought new purses. I, on the other hand, bought a very nice Honda racing jacket for RM 60 (about US$16). It's a Formula 1 design, not a motorcycle team jacket, but it's nice anyway! I even bargained successfully (asking price was RM 110). Then we were hot and thirsty, so we went to a food stall area near Merdeka Square and drank big mugs of iced starfruit juice.
I went back to the same stalls Saturday while I was going around on my own and ate a plate of Mee Hong Kong (delicious!), which consisted of lightly fried noodles, broth, some hacked beef and chicken, the tiniest baby octopuses I've ever seen (tender and tasty), and assorted veggies, including some finely chopped cauliflower and a little fresh spinach. I also had a glass of limeade (very sweet) and a giant bottle of water. Total bill: RM 7, or about $2.
Still working on the photos. I went to Masjid Jamek (a famous mosque) and also to the National Museum. Masjid Jamek was the first mosque I had ever seen back in 1995 when I visited Malaysia for the first time. It looks the same as I remember it, but the area all around it has changed dramatically -- especially because of the addition of the LRT elevated train, which has a station nearby.
Because sexual performance is often a big part of a man's self-esteem, experiencing erectile dysfunction (ED) can be devastating not only to a man's sex life, but to his entire sense of being. Men with ED can become uncertain of themselves and avoid intimate situations with their partners; this only increases the pressure and anxiety associated with a condition which is often treatable. Penile prosthesis: The wound is checked 7-10 days after the operation to assess for signs of infection. The urine is also examined for signs of infection. Antibiotics are administered for 5-7 days following discharge. Surgical intervention for a number of different conditions may remove anatomical structures necessary to erection, damage nerves, or impair blood supply. Complete removal of the prostate gland or external beam radiotherapy of the gland are common causes of impotence; both are treatments for prostate cancer. Some studies have shown that male circumcision may result in an increased risk of impotence, while others have found no such effect, and another found the opposite. viagra online canada Some of the symptoms of depression include: The peptide Tx2-6 from the venom of the Brazilian wandering spider has recently received media attention as a potential prototype for new drugs targeting nitric oxide signaling. These drugs work by preventing the breakdown of PDE5, which is an enzyme in penile smooth muscle which leads to better function of penile erectile tissue. The PDE5 inhibitors, although not initiating an erection, enhance erections to any given sexual stimulus. High blood pressure High cholesterol Prostate cancer Dr. Peter T. Scardino is chairman of the department of urology and head of the Prostate Cancer Program at the Memorial Sloan-Kettering Cancer Center in New York City. He described the finding as a small but important step toward developing shorter course/higher dose radiation therapies. Note: Clinical practice guidelines are “guides” only and may not apply to all patients and all clinical situations. Thus, they are not intended to override clinicians' judgment. All ACP clinical practice guidelines are considered automatically withdrawn or invalid 5 years after publication, or once an update has been issued. The nice news is that these medicine work nearly instantly, but the dangerous information is that they, as almost all artificial erectile dysfunction medication have side effects that vary from mild to really severe. Waves of sound are beamed through the skin, and although they pass harmlessly through body tissue, they are at just the right pressure to smash up kidney stones into tiny sand-like particles that are then passed out of the body in urine. Psychological issues such as anxiety or depression Good nutrition may help improve erectile dysfunction. By increasing the intracellular concentrations of cyclic guanosine monophosphate (cGMP), phosphodiesterase-5 (PDE5) inhibitors such as sildenafil (Viagra), vardenafil (Levitra), and tadalafil (Cialis) have been used therapeutically to treat erectile dysfunction (12), pulmonary hypertension (13), and cardiac hypertrophy (14). More recently, they were shown to induce apoptosis in different human tumors such as colon carcinoma and chronic lymphocyte leukemia (15, 16). In our mouse models, we show that pharmacologic PDE5 blockade down-regulates MDSC suppressive pathways and restores antitumor immunity. Moreover, our in vitro experiments using PBMCs from multiple myeloma (MM) and head and neck cancer patients suggest that the same mechanisms found in mice are also present in humans and demonstrate a possible role for PDE5 inhibitors as an immune adjuvant in the clinical setting. This is the first demonstration that PDE5 blockade exerts an indirect, immune-mediated, antineoplastic effect through inhibition of MDSC-mediated immunosuppressive mechanisms. These findings could establish a new role for PDE5 inhibition as a viable and effective immunological adjunct in the treatment of various malignancies, thereby adding to the growing list of therapeutic applications of these agents. In this paper we show that PDE5 inhibition can significantly overcome the immunosuppressive mechanisms present in a tumor-bearing host to generate immune responses that are similar to (if not greater than) those observed in a non– tumor-bearing, vaccine-primed host (Fig. 2). However, although a CTL response can be elicited, PDE5 blockade is incapable of complete tumor eradication (Fig. S1). Several hypotheses may account for these findings. For example, chronic sildenafil blockade may up-regulate PDE5 expression, making it difficult to achieve complete and long-term pharmacologic inhibition (39). Alternatively, the sildenafil-mediated immune response against the self tumor-associated antigen can predominantly involve low affinity CD8+ T cells incapable of complete tumor cell killing. Finally, the tumor-specific immune response may ultimately result in immune editing of the tumor that escapes immune recognition (Fig. S1, C and D). "What is very hot these days is what we can do to rehabilitate people who develop erection problems after prostate cancer surgery or radiation therapy," Sadeghi-Nejad said. "Anything you can do to increase oxygenation in the penis will help get patients back to normal." The first published efficacy trial of sildenafil involved only 12 patients, but it is the only study that included objective measurements of penile rigidity.20 In the first phase of this study, penile rigidity was measured using plethysmography during visual sexual stimulation in patients taking varying doses of sildenafil or placebo. In the men who took the 50-mg dose of sildenafil, the mean duration of erection was increased by 10 minutes at the base of the penis and six minutes at the tip of the penis compared with placebo. The second phase of this study involved a diary of erectile activity in which 10 of 12 patients reported improved erectile activity while receiving sildenafil. Corpus Cavernosometry